COMBINED LIPIDOMIC AND PROTEOMIC ANALYSIS OF ISOLATED HUMAN ISLETS EXPOSED TO PALMITATE REVEALS TIME-DEPENDENT CHANGES IN INSULIN SECRETION AND LIPID METABOLISM.

Combined lipidomic and proteomic analysis of isolated human islets exposed to palmitate reveals time-dependent changes in insulin secretion and lipid metabolism.

Studies on the pathophysiology Disposable Bowls of type 2 diabetes mellitus (T2DM) have linked the accumulation of lipid metabolites to the development of beta-cell dysfunction and impaired insulin secretion.In most in vitro models of T2DM, rodent islets or beta-cell lines are used and typically focus is on specific cellular pathways or organs.Our

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The effect of microwave stabilization on the properties of whole wheat flour and its further interpretation by molecular docking

Abstract In order to stabilize the whole wheat flour and extend its shelf life, microwave was employed to heat the wheat bran to inactivate the lipase Hat in this paper.The effects of microwave heating of wheat bran on the lipase activities, gluten properties, dough properties and storage stability of the stabilized whole wheat flour, and the quali

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